The ASME BPE (Bioprocessing Equipment) is one of the world’s most important standards for hygienic plant and components in the pharmaceutical, biotechnology and food industries. This presentation provides an overview of current changes, extensions and trends within the ASME BPE guideline. It covers selected normative updates and their implications for the planning, design, manufacture and qualification of plant and components. The presentation is aimed at engineers, plant manufacturers, operators, quality managers and anyone working with hygienic processes. A basic understanding of hygienic design is an advantage, but not essential.